glucosamine and msm!

kellyeaton

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is this product ok to feed a horse with no probs with joints. just as a prevenative to keep him flexible loose and supple etc?
 
I never found any of these supplements to be any good with any of my horses that had arthritic changes or navicular syndrome issues.

As a biologist I am highly sceptical that they could work.
Without going into loads of detail or wishing to open a huge can of worms here, there is certainly is a great deal of research that points to their effects being negligible or not statistically significant.

Mostly I think its just more money down the drain, or into the coffers of huge numbers of charlatans and quacks out there trying to make as much money out of horse owners as possible.

As I understand it, digestive process in most mammals would ensure that these products which are essentially foodstuffs, are broken down into their constituent parts, proteins, fats and sugars by the digestive system, and are thereby largely rendered ineffective for what it is claimed they can do.

Medicine and drugs products are obviously different, but we are not taking about these, what we are talking about are what are known loosely as nutri- ceuls, as opposed to pharmaceutical products that have to be prescribed.

Total waste of hard earn cash in my opinion.
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I don not agree I have seen many studies which show that these products work however there are some golden rules to follow to ensure you are not waisting your money:
Studies have shown that these parts make it in to the joint
1) studies have shown that you need both glucosamine and chondroitin to have a positive effect
2) Glucosamine HCL is much better than the sulphate version as that contains so much extra salt
3) MSM is a anti-infamatory, which can be good and bad (eg do you always take pain killers if your back hurts)
4) ensure you buy from a reputable company as so many products do not meet there label claims.

I have used cosequin for my horse for the last 4 yrs, and when I tried him without it he went lame so I think it works, however I cant afford the vets price and so I get it from america, however please do not use Cortaflex (it probably has a effect due to the MSM but when you read the lable it has not glucosamine or chondrotin just the sugars that they think may make them.
 
Lui23456, Yes, I think you are making a valid point. The combination and the proportions of the known active ingredients are relevant.
Like it is no good taking calcium tablets supplement for arthritis in humans, unless you are also taking Slow K (potassium) at the same time.
Its no good taking glucosamine without chondroitin sulphate because they are general found in the body in a particular biomolecular combination. These ingredients have to be in a molecular form recognised by the body to be even remotely effective.
You cannot just pour these things into the system and expect the body to manufacture new cartilage say, but this is what some people think will happen.
If that was the case, we could just grow all sorts of new body parts whenever the old ones wore out!!!
Perhaps it is best to address the biomechanical causes of a problem,like say not doing lots of circle work with an animal that does not have ideal conformation for the job, or just choosing not to do concussive work like trotting on rough tracks.
An holistic, conservative approach may yield a better long term effect than just resorting to what to me seems the `easy fix route`.
 
I had a mare with pedal ostitis due to poor conformation of the front limbs, she had arthritic changes to the outer edges of the pedal bone. 'Bute made her sound, Devils Root Claw had no effect, Cortaflex did nothing at all - what a surprise in view of what Lui23456 says, yet the day she was shod in NB shoes she went sound ands has remained so to date, - well into her 22nd year.
 
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