Investigation of the Relationship between Plasma Nesfatin-1 Levels and Neutering in Dogs

skinnydipper

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Neutering, which includes orchiectomy for males and ovariohysterectomy for females, is a common practice in dogs to control populations and prevent health issues. Despite its benefits, neutering can lead to hormonal changes that may contribute to a tendency toward obesity over time. Our study investigated how neutering in both female and male dogs affects hormones involved in metabolism and appetite regulation, specifically nesfatin-1, serotonin, dopamine, TSH, and T4. We observed that neutering decreased levels of nesfatin-1, serotonin, and T4, and increased TSH levels in both genders. These hormonal changes could be part of a mechanism contributing to the higher risk of obesity observed in neutered dogs in the long term.

 
I've noticed that with my mal - I have to stay on the ball with his weight, plus he'd eat until he exploded if I let him. It was part of the agreement when I adopted him that I'd have him done. And to be honest, I think he'd be much more of a handful entire. The husky was already neutered when I adopted him, but seems to regulate himself pretty well.
 
Well I suppose sex is of no interest any more. That leaves food and play. Yes, I have had to be careful with my GSD, but have attained a good weight for him now that can be kept, he has enough to eat and plenty of exercise.
 
We have 3 spayed Lab bitches. The 2 working bred sisters are now 5 yrs old, still slim with visible ribs and not greedy at all. The rehomed, much bigger type always seemed to be hungry before she was spayed. Since then we have had to be very careful with her diet to manage her weight. She would eat until she burst given half a chance.
 
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