Resistance to Equest and Equest Pramox Wormers

If you use the same wormer constantly without variation then they will build up a resistance to it. The only problem Ive had with Pramox though is my TBx having a very nasty reaction to it
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there is no resistance to moxidectin in any species of animal unless there is a very new report in which case can you direct us.

There is reistance to ivermectin, pyrantel and fenbendazole.
 
Well I certainly hadnt used it for 2 yrs. This yr I decided to do the equest/equest pramox routine again for my 5. They were all wormed on 27/5. One mare is now away on schooling livery and they have noticed her passing fresh roundworms. I said the usual - sorry - mortified- but my horse was wormed bla. She said funny that - as she had seen reports regards resistance.
I always thought that if you alternated drug types year on year you shouldnt get a resistance.
Just a bit peeved to find that the worming of 5 at around £60 may be seeminhly pointless, thoughts?
 
Moxidectin is the active ingredient in Equest and Equest Pramox and there is no confirmed resistence in horses. There is resistance in large roundworm with Ivermectin (Eqvalan, Eqvalan Duo, Noromectin, Vectin, Eraquell, Biomectin, Maximec, Animec and Equimax). There is no confirmed resistance in Praziquantel (Equitape, Eqvalan Duo, Equimax and Equest Pramox. There is reported resistance in small and large redworm for Pyrantel (Strongid P, Pyratape P, Embotape and Exodus). There is widespread resistance in small redworm for Benzimidazole (Panacur, Panacur Equine Guard, and Telmin). So its best to go with the Equest and Equest Pramox programme really! You can get the vet to test for resistance on your yard I think.
 
I am on a large yard and our veterinary practice came in about 2 months ago and gave a talk about worming...

Apparently at some point there will be a resistance to the equest programme, so we have switched to the Liverpool System which means we now send of dung samples to test rather than worming. Bit scared to as how its going to work because it obviously relies on field management! But so far its all going ok!
 
peeved wouldn't be the word I would use, I see this as a very serious problem.

I would suggest that it is possible that the mare has picked up a burden since treatment on the 27/5. I would contact your vet on this one and they may have to pass it on to fort dodge or similar, in case they maybe had a bad batch, was wormer in date and given at correct dose?. resistance testing can be done fairly simply. I really hope that you haven't got moxidectin resistance as it is something we really don't need and could be a major problem for you.

Speak to your vet.
 
I remember a few years ago having a horse very ill and finding it had worms , we had been using Eqvalan. I wrote to the company and was told they had no resistance problems [ which is obviously been proved wrong now] They were not interested at all in our horse.
Luckily now we have more choice but don't expect the worming company to be interested!
 
fort dodge make it.

they will most probably suggest it was given at incorrect dose without back up information from your vet
 
Ester - I get what you are saying but the spec says 13 weeks protection. I will definately speak with the vet and Fort Dodge I think - and will now have to get all horses dung tested - which I do occaisionally anyway. Humph - you dont expect to adequatley worm your horses and find they have worms!
 
We used Equest last year. We used the Pramox in Autumn 2008, then Spring 2009, and Autumn 2009, it shouldn't have been used the 3rd time it was a vet mess up. Basically last Autumn one horse was blood tested after having coliked and was found to have a bad burden of tape worm. Some other horses were then tested and also found to have tapeworm. There was then a mess up and we ended up using the same wormer (Pramox) which had clearly not worked previously.

Another tapeworm wormer has since been used problem solved. (sorry if this is easy to read, got a lot going on at the mo)
 
Fort Dodge Animal Health
Address: Flanders Road
Hedge End
Southampton SO30 4QH
Telephone: 01489 781711
Fax: 01489 788306
I'm guessing your mare picked up worms where she is now or after worming, seems odd.
 
With Equest and Pramox, you should get 12 weeks protection. However, if the batch was out of date, or if your horse had a large worm burden when it was used in May, then you would not get the ongoing protection. This is information that I got from my vet, if the worming dose is used to kill off a worm burden then there is less that goes into the system. You would only know if that's a possibility if you did a worm count back then.
 
I have just called Fort Dodge, who will get their vet to call me back. Whilst its classed as a 12/13 week wormer, it will only protect against roundworms for two weeks - on the assumption that the worm levels will not have built up enough in the 13 weeks to cause a problem.
I know my instructor who is schooling her intends to use exodus on her today.
I will certainly be getting worm counts done again - as I thought I had done everything to ensure my horses were protected i.e. changed drug types/groups annually, wormed as per directions/regularly with correct dose.
 
yup thats fine, I think but am not 100% that resistance has been found in other countries. The problems come as I am sure you can understand if you end up with multi resistance populations ie if you have moxidectin and pancur type wormers you are left with nothing to treat your horses with that are infected with for encysted redworms in the long term in order to stop this spreading the horses are PTS and the land not used. this has happened on sheep farms in the south west (2 I think) and also a horse farm in mexico. (but don't panic just yet)

I know in the cases of farmers that have taken things back to the company incorrect administration has been blamed but I think that the company (not fd) were did take samples for doing resistance testing to check.

I would speak to both fort dodge and your vet.

Re your worming programme have you introduced any other horses to your herd recently

The schooling livery should also not allow this horse out on pasture until the matter has been clarified as they risk infecting their pasture too.
 
galaxy23, did you report that?

tapeworms should not be resistant to pramox.

furryears, I wondered if that might be the case, I wasn't sure how they worked it out weeks wise.
 
Ester, unfortunatley a couple of mine have "been in and out" recently to go on schooling livery as I am still crocked after a nasty accident in Oct 07. Humph. I always ensure my worming is up and together but clearly in this case it is not good enough.
I guess it looks like the answer is even if they are wormed they are not strictly protected. When they have been out on livery they have always been on part stable and part individual turnout.
 
No idea, I'm not the owner or the yard manager, nor were the vets dealing with it my vets. But the problem was discussed with the vets, so they were aware. There's no doubt that it definitly didn't work though.
 
I don't think there is. I thought this was about the only one without resistance.

However I do know a man who would have the inside track on this. I'll see if I can get him by txt!

Incidentally my mare is 1 1/2 years into the Equest program and was recently worm counted after a couple of mild colic bouts.

Blood and stool samples came back with a zero count so that's good enough for me.
 
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No idea, I'm not the owner or the yard manager, nor were the vets dealing with it my vets. But the problem was discussed with the vets, so they were aware. There's no doubt that it definitly didn't work though.

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There is a SARSS scheme for this very purpose. It stands for Suspected Adverse Reaction Surveillance Scheme and covers environmental incidents and adverse reactions in both animals and humans relating to animal medicines. If you go back to where you bought it from they can fill in a form for you.
 
Resistance has been reported in the US where Equest (Quest over there) came onto the market before it did here. Ironically, good old Strongid-P which has been around since the year dot showed the least resistance. Luckily for me, this is all I can use as my mare is not allowed to have anything else due to a medical condition. Good poo-picking is essential though.
 
I have been doing the worm count system for 5yrs now, I worm for tapeworms twice a year and test for worms twice a year, in 5yrs I have only had one high count in an old horse. As well as saving me money and I know if my boys have a problem with worms.
 
i worm only to times a year now and poo count the rest less change of the horse and worms getting resistance to it and less chemicals being pumped in to the horse!
 
There is NO known resistence to these products (unless it is very very recent) but there is to every other wormer.In time, a resistence will develop, partly because of people under estimating the weight of their animals and under dosing.
 
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