Synequin or Corsequin?

Holly Hocks

Holly Hocks

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My mare has been diagnosed yesterday with bone spavin in her near hind hock. I currently give her and have been giving her for sometime, Aviform Suppleaze Gold. However I am now thinking of giving her something different which might be better. I've read good things about Synequin and Corsequin. Has anyone used either of these and did they see a difference using then? Thank you.
 
A few years ago when I needed something the vets were recommending Synequin above all the others as the most efficient and value for money and it did work very well, it cleared it up completely so I would go with that again if needed. Cheapest place for it then was Beeston Animal Health, don't know if it's the same now.
 
Girl at yard used Corsequin for afew years on her old boy, bought it online as it was cheaper. The horse did well on it, now she has stopped using it to cut costs and she has spent more on vets bills, as his condition - arthritis has flared up. So yes I'd say try it and if it helps don't stop suddenly.
 
I've just been searching on line at the different products and the synequin and cosequin actually have less of the active ingredients in them than the Suppleaze gold that I am already using.....does that mean that I should stick with what I am giving her already? Also the Cosequin and Synequin don't contain any Hyaluronic acid or MSM and MSM is supposed to be very good for connective tissue - I really don't know which to give her. I don't mind paying for the more expensive ones, but I can't see the point if they don't contain as much of the active ingredients as the slightly cheaper ones....
 
Chellebean said:
I've got no idea sorry! But I am so sorry to hear Blue has been diagnosed with bone spavin! **hugs***
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Thanks Chelle - it explains the unlevelness that we couldn't get to the bottom of! It's not the end of the world, it's just trying to to sort out which treatment is best - I think we're going to try Tildren first which is given IV by drip - does something to the osteoblasts and osteoclasts - no idea what...if that doesn't work, we'll maybe try Hyaluronic acid and cortisone into the joint. Vet doesn't want to chemically fuse the joint as he said that it can be quite debilitating for the horse and as she's only nine, he said that he would prefer that as a last ditch option.....if fusing the joint is the last option it can be done with work and bute hopefully.
Oh, and she dislocated my shoulder the other night throwing me against the stable wall....first time I've ever lost my temper with her!!
 
I used Cosequin prescribed by the vet combined with rest for a horse with fetlock damage that failed flexion test - after 3 months passed flexion test. Cosequin has published results from clinical trials proving it does work.

Holly Hocks said:
My mare has been diagnosed yesterday with bone spavin in her near hind hock. I currently give her and have been giving her for sometime, Aviform Suppleaze Gold. However I am now thinking of giving her something different which might be better. I've read good things about Synequin and Corsequin. Has anyone used either of these and did they see a difference using then? Thank you.
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Holly Hocks said:
Thanks Chelle - it explains the unlevelness that we couldn't get to the bottom of! It's not the end of the world, it's just trying to to sort out which treatment is best - I think we're going to try Tildren first which is given IV by drip - does something to the osteoblasts and osteoclasts - no idea what...if that doesn't work, we'll maybe try Hyaluronic acid and cortisone into the joint. Vet doesn't want to chemically fuse the joint as he said that it can be quite debilitating for the horse and as she's only nine, he said that he would prefer that as a last ditch option.....if fusing the joint is the last option it can be done with work and bute hopefully.
Oh, and she dislocated my shoulder the other night throwing me against the stable wall....first time I've ever lost my temper with her!!
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Ouchie ***hugs***

I hope it heals soon xxx
 
Use synequine on my 6 yr old and Riaflex on my 16 yr old synequine on vets reccomendation for hock thickening seems to work
 
I have been given synequin. Notice no difference but then my horse has not reacted to any treatment for his bone spavins and is off to get them surgically fused on the 14th and if that doesnt work god knows. Depending on your insurance company they will pay for supplements if recommended by the vet
 
Holly Hocks said:
That's what I thought which is why I'm a bit reluctant to change....mine is expensive, but not as expensive as the Synequin/Cosequin....
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My vet always recommended Synequin. After I got Riaflex Complete, he compared the specs and admitted that the Riaflex Complete was actually HIGHER spec than Synequin at a third of the price. Guess what he recommends now?:D
 
Thanks Janet - I was searching threads earlier and I found your previous post about the Riaflex complete, but I think the Aviform Suppleaze Gold is the same spec, or even slightly higher....I'll have a look again and do a comparison. I'll try anything for this mare!
 
Janet - just done a comparison - the Aviform has slightly more Glucosamine and Chondroitin, but the Riaflex has more MSM in and they have the same amount of HA in - now I'm confused!
 
MiCsarah said:
Id stick with the one your on. If your that worred about msm you can buy that on its own
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Yes I think you're probably right. I'm hoping the treatment we're going to start might help, as it's very mild lameness so not too advanced, but you just never know....
 
I know someone who used cosequinn for a very slight pelvis problem and it's made the world of different, and i've also known and worked with a horse that was on synequine for a stifle injury. tbh i don't know the difference but both worked very well for the horses :)
x
 
emmalu said:
I used Cosequin prescribed by the vet combined with rest for a horse with fetlock damage that failed flexion test - after 3 months passed flexion test. Cosequin has published results from clinical trials proving it does work.
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Having said this, Ive just tripped over a thread
http://www.horsegroomingsupplies.com/horse-forums/reviews-on-corta-flex-ha-supplement-102073-2.html

which casts a bit of a cloud on the cosequin claims: (quote below)

"Well, for those of you that know me, I'm a scientist by day. I work for a large pharmaceutical company.

I did some checking on the Cosequin claims, and wow, I must say, I'm disappointed. I read the pharmacokinetic study in its entirety (not just the little 1 paragraph blurb on the Cosequin website). Pharmacokinetics ("PK") is basically the study of what happens to a drug or molecule when it enters the body--how fast does it get into the system, how fast does it break down and clear the body, etc.

Anyway, to make a long story short, they had to orally dose the horses at 5-10 times higher than normal just to see evidence of the glucosamine HCl in the horses' plasma (basically, the bloodstream). Even at that high dose, the bioavailability of the glucosamine was only 2.5%. In the human pharmaceutical industry, we shoot for at a bare minimum of 20% bioavailability for oral drugs, and most good drugs are closer to 50%+. The chondroitin in the Cosequin, however, did have 22% bioavailability, so that's better...but still not great.

The other studies they cite are ex-vivo studies, meaning they were performed in the lab, not on live horses, but on tissue samples. That does not prove that oral dosing gets the product to the target tissues. It only proves that IF the product gets to the target tissues it works. Problem is, the PK study already showed that a small percentage of the product ever makes it into the system in the first place. AND what does make it into the system gets widely dispersed throughout the body, NOT just to the joints.

As far as clinical proof of Cosequin working in horses, they cite only 2 studies, one of which was open label, which means the researchers assessing the horses knew which horses were receiving what (glucosamine/chondrotin vs. placebo). IMO an open-label study is useless, as investigator bias is very possible. The other study was double-blind, which means the researchers did not find out which horse received what until after they completed their data analysis, so that one is more legit. Unfortunately, I don't have access to the full-text double-blind study, so I couldn't read it in detail.

Cosequin cites a lot more evidence in dogs, though. Interesting that the glucosamine HCl has a 12% bioavailability in dogs vs. 2.5% in horses. Whole different animals with different digestive systems and metabolic processes."
 
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Thanks Emmalu.
I've just ordered some more of the Suppleaze Gold which I was using in the first place! I've sent a couple of e-mails to other companies which don't put the levels of the ingredients on their website asking for the levels, so will await a reply from them.
 
No probs. Am now thinking of moving from cosequin...

PS can I join your TB injury hotline clique ??

Overnight on friday my TB tripped over himself ripping off and bending front and back shoes, with puffy ankle and tender back. I just had the back man out on wednesday!!!!
 
emmalu said:
No probs. Am now thinking of moving from cosequin...

PS can I join your TB injury hotline clique ??

Overnight on friday my TB tripped over himself ripping off and bending front and back shoes, with puffy ankle and tender back. I just had the back man out on wednesday!!!!
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I think you should definitely join!! It's not like it's the last injury he'll have... he's a TB after all!! Since I bought the mare last April I haven't had one month without a vets bill....
 
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