Article about Osphos & Tildren / Delayed healing in Young horses

[BunnyDog]

I didn't know if you all kept tabs on articles from this side of the pond, but this came out yesterday and it's a really interesting and disturbing find about two popular medications that are heavily marketed in a lot of horse magazines by their makers. Osphos especially and the doctor who's speaking about this is a vet of very high repute based in Kentucky. He is the "go to" guy with race horses with issues in the USA.

https://www.paulickreport.com/horse...price-pay-bisphosphonate-use-delayed-healing/

That article was disturbing enough that I started digging and saw this article from a year ago and there were early mentions of concerns in young horses then as well.

https://thehorse.com/19618/what-we-know-and-dont-know-about-bisphosphonates/


And going even back to 2011, they saw delays in the healing of a research rat's ulna....

http://onlinelibrary.wiley.com/doi/10.1002/jor.21464/pdf

Long story short, be careful using this in younger animals. And really talk to you vet about doing their research if they recommend it. It's possible that they may not be up on this newer release of information.

Emily

 

[Birker2020]

I know about death of the jawbone in humans as my Dad was offered this treatment to minimize the pain in his bones and delay the spread of cancer to the bones when he was diagnosed with bone cancer which was secondary to prostate cancer. He was supposed to attend a dentist to check his teeth/jaw prior to the infusion but was too ill to make it out of the car and into the dentists and so sadly didn't get this treatment as they couldn't do it at home.

He had an oral form of bisphosphonate but for some reason they stopped giving it to him and then re-started it again by which time the cancer had really taken a hold on his bones and he died soon after.

I can remember speaking to one of the consultants at the hospital about the human equivalent of Tildren and explained that they used it in horses which the consultant was very interested in and quizzed me about my friends experience with it on her horse. He was about 10 or 12 when he was given it but didn't have a dental check up, the only side effect he had if you can call it that was that he wee'd for England, his bed was soaking wet the following day which apparently happens to some horses - I can remember my friend telling me she had about a weeks worth of urine from him in 24 hours!

I didn't realize the jawbone problem happened to horses too. Very interesting article. Thank you for sharing.