Bute V Danilon

iduck

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5 June 2013
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Hi everyone,

I was just thinking about bute and danilon and wondering what the main similarities and differences are?

Thanks!
 
i dont know the exact differences but i know my vet always prescribes danilon over bute for my horse as he has a sensitive stomach and she says its better for those with ulcer/gut issues.
 
Bute is phenylbutazone, danilon is suxylbutazone (sbz). Theoretically bute breaks down into sbz so there's less metabolisation required. Sbz is also generally more palatable. Not sure how much evidence about sbz being better for guts than bute but that is generally believed to be true.
 
Both 'Bute' (Phenylbutazone) and Danilon (Suxibuzone) are Non-steroidal anti-inflammatory drugs (NSAIDS) so both can cause gastrointestinal problems and more rarely renal problems with prolonged use.
They are both banned substances competition wise and both rule a horse out of entering the food chain.
Bute is cheaper than Danilon, nowadays my vet seldom prescribes either, intead we have Metacam - which is much more expensive than either the other two!!!

My horse was on a sachet of bute daily for several years without ill effect and whilst suffering a particularly bad bout of laminitis he was on 4 sachets a day. Happily his arthritis seems to have stabilised and he no longer needs drugs to keep him comfortable.
 
Pro Dynam is a heck of a lot cheaper than Bute and Danillon and does exactly the same job - check it out.
 
One important difference is that most horses will eat danilon in their feed but don't like the taste of Bute as it's bitter so harder to get into them.
 
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