chronic granulomatous pododermatitis

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TPO

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Fully expecting this to sink without a trace!

Just in the off chance anyone has any experience and/or knowledge about chronic granulomatous pododermatitis.

I've read all that Google scholar has to offer.

TIA
 
More commonly known as canker?? my vets had one in for most of last summer being treated, I know it was extremely problematic, that the vet treating spent hours researching and that when I last went there it was looking fairly positive, the horse was being shod that day and the results were promising but I do not know whether it was resolved as I have not been there recently and not my horse to ask about.
If you need help they may be able to give you some ideas, pm and I can send you a contact number.
 
If it's canker you are talking about I think that research is pointing towards a link with the bovine papillomavirus.

"Recent research has shown that the DNA and RNA of bovine viruses (papillomaviruses), which can cause tumours, have been detected in canker tissue samples, whereas no viral DNA was detected in horses without canker lesions.1 A short communication recently published in Veterinary Record documents a new and promising therapy for canker using a topical formulation of cisplatin chemotherapy, aimed at reducing the length of hospitalisation and short-term recurrence of the disease.2 Cisplatin is one of the most potent chemotherapy agents used in human and veterinary medicine and intralesional cisplatin chemotherapy with and without surgery is a well-documented and successful therapy for common equine skin tumors (sarcoids). It works by binding to certain sequences of DNA/RNA, making it unable to replicate.

Ten horses (19 hooves) diagnosed with canker were included in the study. Hooves were thoroughly cleaned, trimmed and kept in disinfectant bandages until surgery, when affected tissues were removed. If healthy tissue appeared a few days later in the absence of any suspected canker, the topical cisplatin therapy was started. This included 10 applications of cisplatin paste, made up of cisplatin injection solution, EucillinB crème and metronidazole-saccharose (two antibiotics). Treated hooves were bandaged until a layer of horn had formed or the hooves were fitted with a treatment plate. Horses were kept in hospital on an average of 32 days and follow-up investigations (between 0 and 14 months) found that nine of 10 horses had not any recurrence of the infection."
 
Thanks for the replies.

Apparently not canker as scrapings were taken and examined previously (at least that's what original practice told me but they weren't so great with the truth so they possibly didn't even do that). It doesn't present as canker either and not displaying any external characteristics. Not a typical candidate for canker due to OCD standards of management and hygiene either!

There have been chronic abscesses from the frog. Trimmer ( forwarded her vet's email) is a scientist type bod and found similar papers linking it to BPV/sarcoids/benign tumours ( well hopefully benign!) as those mentioned above.

I've had a complete nightmare with vets who've misdiagnosed and not been so great with the truth... Finally getting somewhere with new vet practice who I'm very thankful for. X-rays on Friday will hopefully reveal more.

Might be back after results. Thanks again.
 
It hasn't been great! The original practice made it 100x worse; but hopefully third times a charm with practice no.3!

I will do. You never know when someone else might google it!
 
Not specifically but I got bloods done, at my insistence, with original practice.

He's on a "barefoot" diet and is supplemented with Pro-Balance/Pro-Hoof/Forage Plus Healthy Hoof (not at the same time but I've tried a variety). He also gets extra copper (& zinc) in his diet.

I've been in contact with Sarah at FP previously re the addition of minerals to balancers.
 
Just an update to say that the x-rays confirmed the vet's suspicions but thankfully it's not in the bone.

Horse going in for surgery to remove it and it should be a relatively small incision so hopefully quick to heal.

The vet asked what I'd managed to find out as there isn't much info out there due to the rarity of the condition. I explained that most things linked to canker or BPV and he 100% confirmed that it was neither. Thankfully the vet doing the surgery (foreign) has seen, and successfully operated on and treated, a few cases.

Thanks for the replies
 
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