EHV-1. Should I be worried?

beingachicken said:
I just reread and it says EHV, the neuro strain, that it originated at a competition centre and that several horses had died over the past few days. Newbury/wantage area.
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I'm wondering whether this is a case of Chinese whispers. I'm in that area, and our PC branch had a couple of people attend Crofton recently. We've therefore cancelled some rallies and stopped some people attending depending on their contact with those two horses (one rally cancelled as instructor runs livery yard where those horses are stabled). So people are definitely being careful round us, but as far as I know, no cases up here yet.
 
nikicb said:
I'm wondering whether this is a case of Chinese whispers. I'm in that area, and our PC branch had a couple of people attend Crofton recently. We've therefore cancelled some rallies and stopped some people attending depending on their contact with those two horses (one rally cancelled as instructor runs livery yard where those horses are stabled). So people are definitely being careful round us, but as far as I know, no cases up here yet.
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Good! Let’s hope it stays that way!
 
FinkleyAlex said:
I don't think EHV has anything to do with HPV, perhaps you're thinking of HSV (human version of the herpes virus)?
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Thankyou for bringing that up...I have been stung by acronym hell!

I am referring to human herpes infections having been shown cleared in patients using hot water extracted Trametes mushrooms, while that information also pertains to other common debilitating.

Often times the studies are studying h1n1, herpes, human papillomavirus, west nile, HIV virus etc altogether. All of which are shown to be inhibited in viral activity by various mushroom strains, with turkey tail exhibiting the highest therapeutic actions.
The alcohol soluble constituents of mushrooms have been minimally studied, in comparison to hot water extracts of polysaccharides yet their usefulness is known, and hence why a ‘double extraction’ tincture of the mushrooms is the preferred medicine as it contains all immune-regulating compounds.

“
In this study, we investigated the in vitro antiviral activity of the mycelia of higher mushrooms against influenza virus type A (serotype H1N1) and herpes simplex virus type 2 (HSV-2), strain BH. All 10 investigated mushroom species inhibited the reproduction of influenza virus strain A/FM/1/47 (H1N1) in MDCK cells reducing the infectious titer by 2.0–6.0 lg ID50. Four species, Pleurotus ostreatus, Fomes fomentarius, Auriporia aurea, and Trametes versicolor, were also determined to be effective against HSV-2 strain BH in RK-13 cells, with similar levels of inhibition as for influenza. For some of the investigated mushroom species—Pleurotus eryngii, Lyophyllum shimeji, and Flammulina velutipes—this is the first report of an anti-influenza effect. This study also reports the first data on the medicinal properties of A. aurea, including anti-influenza and antiherpetic activities. T. versicolor 353 mycelium was found to have a high therapeutic index (324.67), and may be a promising material for the pharmaceutical industry as an anti-influenza and antiherpetic agent with low toxicity.”

https://www.researchgate.net/public...d_herpes_simplex_virus_type_2_in_cell_culture


HPV and HHV human herpes virus both have strains that can cause cancer in humans. Herpes in humans is not just one strain that causes ‘cold sores’.
Integrative oncologists oftentimes use a multi-strain mushroom extract blend as conjunctive cancer therapy, due to medicinal mushrooms remarkable ability to regulate the immune system. Inhibiting an over-stimulated one, and boosting a weaker immune system.

This quote is from an article claiming a patent for the alcohol compounds of medicinal mushrooms:

“
Medicinal mushrooms have been used for thousands of years for a wide assortment of ailments. Traditionally the mushroom fruitbody has been used. Scientists have extensively studied extracts of the fruitbodies over the past decades. Although numerous papers have been published showing hot water extracts of mushrooms and their mycelia can activate immune systems and can be anti-inflammatory, comparatively few have elucidated the benefits of the alcohol fractions. The current invention describes novel contributions to the field of medicinal mushroom research, particularly discoveries pertaining to antiviral activity of alcohol extracted mushroom mycelium and the active constituents contained within them.

Scientists are now discovering that viral infection challenges and degrades the immune system in multiple ways including inflammation, which can lead to cellular damage from free radicals, a cofactor in carcinogenesis, and to cancers caused by oncoviruses. Worldwide, the World Health Organization (WHO) International Agency for Research on Cancer estimated that in 2002 17.8% of human cancers were caused by infection, with 11.9% being caused by 1 of 7 different viruses. The 7 viruses that are known to cause cancer include three herpes oncoviruses: Epstein-Barr aka human herpesvirus 4 (HHV-4); human herpesvirus 6 (HHV-6) and human herpesvirus 8 (HHV-8). HHV-6 is implicated in the development of lymphomas, leukemia, cervical cancers, Karposi sarcoma, and brain tumors. Other oncoviruses include the polyoma virus that causes Merkel cell carcinoma (MCC), the human papillomaviruses (HPV 16 and 18) which cause cervical cancer, anal cancer, oropharyngeal cancers, vaginal cancers, vulvar cancers and penile cancers; hepatitis B and C, which cause liver cancer; and the human T-lymphotropic viruses (HTLV), which cause T-cell leukemia and T-cell lymphoma. Four HTLVs are well known. HTLV-1 and HTLV-2 are involved in epidemics, infecting 15-20 million people worldwide.”

https://patents.justia.com/patent/9931316
 
I've seen the Abingdon RDA Group have posted on Facebook an hour or so ago that they are on lock down following another case in Wantage that they were told about from their vets so unfortunately it might be true about another case in Wantage.
 
Squeak said:
I've seen the Abingdon RDA Group have posted on Facebook an hour or so ago that they are on lock down following another case in Wantage that they were told about from their vets so unfortunately it might be true about another case in Wantage.
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Our yard is in Reading and has just gone into lockdown due to some local cases, so I assume that's Wantage.
 
I’m in Oxfordshire and our vets put out a note to say most venues in lock down but the only confirmed cases so far of EHV was in Hampshire. Which were fatal. They didn’t say we have had any confirmed cases in Oxfordshire although I see the RDA have posted something
 
ester said:
I'm right confused how we have gone onto mushrooms on a post about EHV-1 (EHM).

What happens when you eat the product rather than applying it directly to a viral infected cell
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Knowledge is the perfect antidote for confusion
 
well yes, the reason we propogate them is for vaccine production.

I'm still confused as to why large quantities of copy and paste text on the invitro effect of fungal extracts on viruses is particularly relevant to the current EHV situation? Could you explain why you think it is, it is your thought process rather than the science that confuses me a little?
 
..which ‘educates’ the immune system with said virus via a minimal dose in the hopes that the immune system will create anti-bodies against the virus.
What’s to stop a vaccine shot turning into a full-blown viral infection in a weakened immune system horse or person?
 
Have also heard of a case in Oxfordshire, but can't find anything official.
I'm north Hampshire, so all quite close. Most places have cancelled events but can't believe Wellington is still operating as normal
 
PurBee said:
..which ‘educates’ the immune system with said virus via a minimal dose in the hopes that the immune system will create anti-bodies against the virus.
What’s to stop a vaccine shot turning into a full-blown viral infection in a weakened immune system horse or person?
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You seem to be struggling with my question.

The ones we make are killed (and bespoke as it happens) so they aren't turning into a viral infection in anything. If you want to go back to talking specifically about EHV and vaccination risks we can do that but you seemed mainly to be talking about other viruses.
 
beingachicken said:
Is Lyford stud the Wantage case? I may screenshot and put it on our whats app group if that’s ok?
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I believe so - it's a public page, so you should be fine to share. I don't want to link it here in case people don't read the whole thread and panic, but their previous post said.... "Good afternoon all. We have recently been advised that there has been a suspected case of Equine Herpes locally. " So it wasn't at their stud, but local to them. x
 
nikicb said:
I believe so - it's a public page, so you should be fine to share. I don't want to link it here in case people don't read the whole thread and panic, but their previous post said.... "Good afternoon all. We have recently been advised that there has been a suspected case of Equine Herpes locally. " So it wasn't at their stud, but local to them. x[/QUOTEi
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I will go look. Thanks. Might put a few more worried minds to rest especially as the message mentioned deaths ?
 
ester said:
You seem to be struggling with my question.

The ones we make are killed (and bespoke as it happens) so they aren't turning into a viral infection in anything. If you want to go back to talking specifically about EHV and vaccination risks we can do that but you seemed mainly to be talking about other viruses.
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The herpes virus strains and other viral infections that are just as difficult to treat, have shown significant inhibition using mushroom extracts primarily for their PSK and beta glucan levels.

I fail to understand how you don’t see the relevance of that information in a thread about herpes strains.

It’s to open up discussion and explore other possibilities that treat these viruses effectively when they occur, as there’s not much currently in the ‘medicine box’ used that is effective.
 
PurBee said:
The herpes virus strains and other viral infections that are just as difficult to treat, have shown significant inhibition using mushroom extracts primarily for their PSK and beta glucan levels.

I fail to understand how you don’t see the relevance of that information in a thread about herpes strains.

It’s to open up discussion and explore other possibilities that treat these viruses effectively when they occur, as there’s not much currently in the ‘medicine box’ used that is effective.
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I am making a wild assumption here but are you anti-vaccine?
 
Yes, that’s a wild assumption.
I’m all for effective treatments for health which alleviate suffering.
 
PurBee said:
It’s to open up discussion and explore other possibilities that treat these viruses effectively when they occur, as there’s not much currently in the ‘medicine box’ used that is effective.
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And are mushrooms effective when given to horses with EHV? You have googled some stuff, copied and pasted huge amounts of text then done an enormous leap to prescribing treatment for a horse with EHV.
 
Yes purbee that's why I asked about the extracts used via digestion given that was your suggested mode of treatment rather than direct application in vitro using cell culture flasks? I was hoping you'd maybe be able to direct me to more info/research given your recommendation.
 
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