Experience of Tildren?

[The wife]

Another vote for it not working for Navicular. Cost a small fortune and was extremely disappointed with the results, considering vet had half promised miracles. Remedial farriery, gel pads, carefully chosen ground and time were our best remedy for it.

 

[Aileen K]

Was the Tildren administered IV? Also, did your horse colic that day?

 

[Twiglet]

The owner tried barefoot with no success (not Rockley but with barefoot specialist). Tarrsteps, i can't remember what the exact outcome was but I think she went into more detail with you?

 

[Aileen K]

MadisonBelle, Thank you. That is what I wanted to know. Except one question: Did you have the vet administer the Tildren IV?

 

[TarrSteps]

MadisonBelle, Thank you. That is what I wanted to know. Except one question: Did you have the vet administer the Tildren IV?

Genuine question, how else would you have it done? As far as I know there is no oral or IM option and I don't think people are allowed to do their own IVs here. Plus, with the risks involved, I would never suggest even attempting to do it without a vet present, even if it was possible.

 

[Aileen K]

1. Of course I would use a vet, done locally or IV.
2. Evidently, there are two ways to administer it now: Locally or IV. The Vet school near here told my vet the IV method is more effective.
3. I am assuming, then that you had a vet administer it IV. I just wanted to verify that.
4. I am fear the colic. The vet said he's give her something to prevent the colic pain. Do you know if your vet did that? Thanks!

 

[TarrSteps]

Interesting, I've never heard of it being used locally. Intra articular injection, I assume? The info sites on the drug don't mention that, so presumably off label. The only options I've seen are one large dose in saline - by far the most common method now - or more numerous small doses.

The vet I've seen do it most often uses an NSAiD and, in at least one case with a horse prone to colic, an anti spasmodic.

 

[TarrSteps]

Have been doing some reading and there has been some experimental, off label use of Tildren intra-articularly. Presumably there would be less risk of colic (I'm totally guessing on that!) but the jury seems to be out on short and long term risks and rewards. There is also some work being done on local IV use, where the injection is done above the affected joint. This is quite a good basic review http://www.equiman.com/forums/ubbthreads.php?ubb=showflat&Number=380731

 

[chestnut cob]

Last horse had spavins and ringbone. Hocks were maintained with steroid injections and we gave tildren when he became unlevel in front. Initially it made a huge difference to him. He was a different horse for about 3 months, really improved. Effect wore off quickly and quite suddenly. Had it a second time and saw no change (for better or the worse). Shame but as has been said above, its not a cure. Its a treatment which gave my horse a new lease of life for a time.

I think tildren is supposed to be pretty effective for arthritic conditions such as my horse had because it inhibits bone remodeling & has some painkillingg effect (correct me if wrong). The problem with 'navicular' is that its a catch all term for 'foot pain' sometimes. If the horse doesn't have arthritic changes then I cant imagine an arthritis treatment helping much.

 

[viola]

Another vote for a complete waste of time, treatment and money - used Tildren IV with absolutely no results on a horse with prior remedial shoeing for "navicular syndrome" in both front feet.
The horse was subsequently rehabilitated barefoot at Rockley in 2010, re-xrayed in 2012 showing no abnormal signs to either of navicualar bones.

 

[Aileen K]

TarrSteps: Thank you very much!

I know some on this thread feel barefoot is the way to go. I am in the US and I don't even know if anyone here has a bardfoot rehab place. I am guessing my vet and farrier would not like this idea, but I might ask them about it for the heck of it.

I am guessing I will stick with the conventional treatments. Of course, this is my favorite horse ever. I have had horses for 30 years and had never even heard of this condition. So sad. Been treating her via farrier, Isoxsuprine, steroid injections into the coffin bone, and joint guard. Tildren is not widely used in the USA. We have to get it from England. I read about it on the internet and asked my vet to check into it. I just fear the colic, but I want to try anything that might help her. Thank you!

 

[Aileen K]

Did your horse have to live at Rockley? For how long? Is he barefoot always now?

 

[TarrSteps]

TarrSteps: Thank you very much!

I know some on this thread feel barefoot is the way to go. I am in the US and I don't even know if anyone here has a bardfoot rehab place. I am guessing my vet and farrier would not like this idea, but I might ask them about it for the heck of it.

I am guessing I will stick with the conventional treatments. Of course, this is my favorite horse ever. I have had horses for 30 years and had never even heard of this condition. So sad. Been treating her via farrier, Isoxsuprine, steroid injections into the coffin bone, and joint guard. Tildren is not widely used in the USA. We have to get it from England. I read about it on the internet and asked my vet to check into it. I just fear the colic, but I want to try anything that might help her. Thank you!

It's my understanding it's still not technically licensed for use in North America but can be used by vets if they fill out the appropriate paperwork and there seem to be many practices using it regularly now. The link I posted is written by a vet in a specialist equine practice in Southern Ontario. Interestingly, there seem to be very few vets here doing anything other than IV systemic therapy but lots of discussion of the alternatives in North America (it took me awhile to work out you were in the US!). Restrictions regarding equine medications are generally more lax there, from what I can see (I'm a transplanted Canadian). Have you asked around on COTH? There are lots of threads about this and related subjects on there.

Pete Ramey is probably the best known "barefoot guru" in the US http://www.hoofrehab.com/index.htm Maybe have a look there if you want to start doing some reading. You could also contact Rockley and see if they have any US contacts.

 

[Aileen K]

OK What is COTH?

 

[meardsall_millie]

OK What is COTH?

A US based forum - http://www.chronofhorse.com/forum/forum.php