It is quite complicated Paula and I would have to type a boring essay on endocrine regulation of calcium and phosphate in order to explain the metabolic effects of Mg++. I'd have to go into energy transfer pathways of Mg-adenosine triphosphate, creatinine phosphate and cofactors such as NAD and NADP and then explain how K+ also affects the whole thing. It's so damned boring.
In so far as it's action on insulin, both protein anabolism and the storage of glucose as glycogen require the concurrent cellular uptake of potassium, phosphate and magnesium. Insulin stimulates the translocation of all three minerals in into muscle cells, and of potassium and phosphate into the liver. Insulin is secreted in response to a carb intake, lowers serum potassium, phosphate and magnesium and is therefore a normal regulator of potassium balance. In insulin resistance, compounded by other factors such as the role of glucose in all of this, would cause life threatening metabolic imbalance. Since in modern human and grazers diets, are mostly poor in magnesium, supplementation of this mineral is required to improve uptake of all three minerals to have an effect on glucose. Yadda yadda...
It's role in chlorophyll is vital but it is not a major compound.
All farmers know they need to supplement Mg in cattle and sheep because the fertilisation of forage, depletes Mg. they could use a magnesium nitrate To replenish but it doesn't Do much good for grass growth really. So farmers use ammonium Sulphate, ammonium nitrate or urea. So, the argument that chlorophyll provides more than enough magnesium to grazers is sadly flawed. Plus, most people keep horses on fertilised soils so, even more reason to add minerals as a lick or feed. All minerals have a role to play which is why they are called essential!
Not that any of the above matters a lot in the great scheme of things. Yes, only 40% of dietary magnesium is absorbed, but you want to be absorbing 40% of a decent amount. If too little then the animal is still deficient. The only reason only half is absorbed is because the lumen can only absorb as food is passing through the intestine, and not all of it can be absorbed before it is passed out of the body.
It's not all biochemistry, it is physiology too. Hope I have managed to send you all to sleep now
It is quite complicated Paula and I would have to type a boring essay on endocrine regulation of calcium and phosphate in order to explain the metabolic effects of Mg++. I'd have to go into energy transfer pathways of Mg-adenosine triphosphate, creatinine phosphate and cofactors such as NAD and NADP and then explain how K+ also affects the whole thing. It's so damned boring.
In so far as it's action on insulin, both protein anabolism and the storage of glucose as glycogen require the concurrent cellular uptake of potassium, phosphate and magnesium. Insulin stimulates the translocation of all three minerals in into muscle cells, and of potassium and phosphate into the liver. Insulin is secreted in response to a carb intake, lowers serum potassium, phosphate and magnesium and is therefore a normal regulator of potassium balance. In insulin resistance, compounded by other factors such as the role of glucose in all of this, would cause life threatening metabolic imbalance. Since in modern human and grazers diets, are mostly poor in magnesium, supplementation of this mineral is required to improve uptake of all three minerals to have an effect on glucose. Yadda yadda...
It's role in chlorophyll is vital but it is not a major compound.
All farmers know they need to supplement Mg in cattle and sheep because the fertilisation of forage, depletes Mg. they could use a magnesium nitrate To replenish but it doesn't Do much good for grass growth really. So farmers use ammonium Sulphate, ammonium nitrate or urea. So, the argument that chlorophyll provides more than enough magnesium to grazers is sadly flawed. Plus, most people keep horses on fertilised soils so, even more reason to add minerals as a lick or feed. All minerals have a role to play which is why they are called essential!
Not that any of the above matters a lot in the great scheme of things. Yes, only 40% of dietary magnesium is absorbed, but you want to be absorbing 40% of a decent amount. If too little then the animal is still deficient. The only reason only half is absorbed is because the lumen can only absorb as food is passing through the intestine, and not all of it can be absorbed before it is passed out of the body. You can call it expensive pee, but if your pee didn't have any minerals in it, you'd be in trouble.
It's not all biochemistry, it is physiology too. Hope I have managed to send you all to sleep now
It is quite complicated Paula and I would have to type a boring essay on endocrine regulation of calcium and phosphate in order to explain the metabolic effects of Mg++. I'd have to go into energy transfer pathways of Mg-adenosine triphosphate, creatinine phosphate and cofactors such as NAD and NADP and then explain how K+ also affects the whole thing. It's so damned boring.
In so far as it's action on insulin, both protein anabolism and the storage of glucose as glycogen require the concurrent cellular uptake of potassium, phosphate and magnesium. Insulin stimulates the translocation of all three minerals in into muscle cells, and of potassium and phosphate into the liver. Insulin is secreted in response to a carb intake, lowers serum potassium, phosphate and magnesium and is therefore a normal regulator of potassium balance. In insulin resistance, compounded by other factors such as the role of glucose in all of this, would cause life threatening metabolic imbalance. Since in modern human and grazers diets, are mostly poor in magnesium, supplementation of this mineral is required to improve uptake of all three minerals to have an effect on glucose. Yadda yadda...
It's role in chlorophyll is vital but it is not a major compound.
All farmers know they need to supplement Mg in cattle and sheep because the fertilisation of forage, depletes Mg. they could use a magnesium nitrate To replenish but it doesn't Do much good for grass growth really. So farmers use ammonium Sulphate, ammonium nitrate or urea. So, the argument that chlorophyll provides more than enough magnesium to grazers is sadly flawed. Plus, most people keep horses on fertilised soils so, even more reason to add minerals as a lick or feed. All minerals have a role to play which is why they are called essential!
Not that any of the above matters a lot in the great scheme of things. Yes, only 40% of dietary magnesium is absorbed, but you want to be absorbing 40% of a decent amount. If too little then the animal is still deficient. The only reason only half is absorbed is because the lumen can only absorb as food is passing through the intestine, and not all of it can be absorbed before it is passed out of the body. You can call it expensive pee, but if your pee didn't have any minerals in it, you'd be in trouble.
It's not all biochemistry, it is physiology too. Hope I have managed to send you all to sleep now
It is quite complicated Paula and I would have to type a boring essay on endocrine regulation of calcium and phosphate in order to explain the metabolic effects of Mg++. I'd have to go into energy transfer pathways of Mg-adenosine triphosphate, creatinine phosphate and cofactors such as NAD and NADP and then explain how K+ also affects the whole thing. It's so damned boring.
In so far as it's action on insulin, both protein anabolism and the storage of glucose as glycogen require the concurrent cellular uptake of potassium, phosphate and magnesium. Insulin stimulates the translocation of all three minerals in into muscle cells, and of potassium and phosphate into the liver. Insulin is secreted in response to a carb intake, lowers serum potassium, phosphate and magnesium and is therefore a normal regulator of potassium balance. In insulin resistance, compounded by other factors such as the role of glucose in all of this, would cause life threatening metabolic imbalance. Since in modern human and grazers diets, are mostly poor in magnesium, supplementation of this mineral is required to improve uptake of all three minerals to have an effect on glucose. Yadda yadda...
It's role in chlorophyll is vital but it is not a major compound.
All farmers know they need to supplement Mg in cattle and sheep because the fertilisation of forage, depletes Mg. they could use a magnesium nitrate To replenish but it doesn't Do much good for grass growth really. So farmers use ammonium Sulphate, ammonium nitrate or urea. So, the argument that chlorophyll provides more than enough magnesium to grazers is sadly flawed. Plus, most people keep horses on fertilised soils so, even more reason to add minerals as a lick or feed. All minerals have a role to play which is why they are called essential!
Not that any of the above matters a lot in the great scheme of things. Yes, only 40% of dietary magnesium is absorbed, but you want to be absorbing 40% of a decent amount. If too little then the animal is still deficient. The only reason only half is absorbed is because the lumen can only absorb as food is passing through the intestine, and not all of it can be absorbed before it is passed out of the body. You can call it expensive pee, but if your pee didn't have any minerals in it, you'd be in trouble.
It's not all biochemistry, it is physiology too. Hope I have managed to send you all to sleep now
'Know it all award' goes to........ Paulag
It is quite complicated Paula and I would have to type a boring essay on endocrine regulation of calcium and phosphate in order to explain the metabolic effects of Mg++. I'd have to go into energy transfer pathways of Mg-adenosine triphosphate, creatinine phosphate and cofactors such as NAD and NADP and then explain how K+ also affects the whole thing. It's so damned boring.
In so far as it's action on insulin, both protein anabolism and the storage of glucose as glycogen require the concurrent cellular uptake of potassium, phosphate and magnesium. Insulin stimulates the translocation of all three minerals in into muscle cells, and of potassium and phosphate into the liver. Insulin is secreted in response to a carb intake, lowers serum potassium, phosphate and magnesium and is therefore a normal regulator of potassium balance. In insulin resistance, compounded by other factors such as the role of glucose in all of this, would cause life threatening metabolic imbalance. Since in modern human and grazers diets, are mostly poor in magnesium, supplementation of this mineral is required to improve uptake of all three minerals to have an effect on glucose. Yadda yadda...
It's role in chlorophyll is vital but it is not a major compound.
All farmers know they need to supplement Mg in cattle and sheep because the fertilisation of forage, depletes Mg. they could use a magnesium nitrate To replenish but it doesn't Do much good for grass growth really. So farmers use ammonium Sulphate, ammonium nitrate or urea. So, the argument that chlorophyll provides more than enough magnesium to grazers is sadly flawed. Plus, most people keep horses on fertilised soils so, even more reason to add minerals as a lick or feed. All minerals have a role to play which is why they are called essential!
Not that any of the above matters a lot in the great scheme of things. Yes, only 40% of dietary magnesium is absorbed, but you want to be absorbing 40% of a decent amount. If too little then the animal is still deficient. The only reason only half is absorbed is because the lumen can only absorb as food is passing through the intestine, and not all of it can be absorbed before it is passed out of the body. You can call it expensive pee, but if your pee didn't have any minerals in it, you'd be in trouble.
It's not all biochemistry, it is physiology too. Hope I have managed to send you all to sleep now
Magnesium and the B-complex vitamins are energy nutrients: they activate enzymes that control digestion, absorption, and the utilization of proteins, fats, and carbohydrates. Lack of these necessary energy nutrients causes improper utilization of food, leading to such far-ranging symptoms as hypoglycemia, anxiety, and obesity.
Magnesium is also necessary in the chemical reaction that allows insulin to usher glucose into cells, where glucose is involved in making energy for the body. If there is not enough magnesium to do this job, both insulin and glucose become elevated. The excess glucose gets stored as fat and contributes to obesity. Having excess insulin can lead to diabetes.
Hope this helps
