High progesterone levels in mares?

Casey76

Casey76

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OK, I want to throw this out for any advice or information.

Due to Tartines abnormal ovaries, I got a hormone panel done to rule out a GTC tumour. Fortunately that was ruled out, however, her progesterone was above the ULN (tested as 22.9ng/ml, ref range 1.0 - 15.0ng/ml)

Any potential issues with this? Any risks associated with it?

I'll be talking to my vet next week when T has her normal blood panel done, but I'd like to understand a bit more before I bombard my vet with questions.

TIA :)
 
Is it just a large ovary or does she have a big folicle in it? if I remember rightly I would guess that it may stop her coming in season (its what is in regumate) as its produced by the cl after the mare has ovulated. if it is always high it may mean that the cl will stay in place. I think my first question to the vet would be what happens after she ovulates as in does the uterus produce enough prostoglandin to get rid of the cl and therefore stop the progesterone or what other things could be causing it.
 
Thanks for the reply :)

If I get them the right way round, Tartine's left ovary is about the size of a large clenched fist, is multilobar and didn't show any particular activity on the ultrasound (hence the reason for the GTC tumour test). Her right ovary was a little smaller with one large follicle which looks either encapsulated or encysted.

She generally has fairly silent seasons, though at the moment she is showing a lot. However apart from squirting and winking she really doesn't have any character changes.
 
although I am not a vet I am very interested in reproductive issues and that is a different one to normal :) I would see what the vet says and possibly have a repro specialist look at her. I have known pregnant mares squeal squirt and wink so it may or may not be a proper season. they can inject prostoglandin which would normally help shift a persistant cl but if the folicle is encapsulated in some way it may not be successful. please please post back with what the vet says about it and does as for me it is a really interesting case :)
 
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