HORSES WITH WINTER LAMINITIS - PLEASE READ

muff747

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Winter lami in a Cushings horse or pony is not "caused" by lush grazing, frosted grass etc, although that won't help getting the lami under control.
I learnt this when my TBx was diagnosed in 2009 with Cushings. I was shocked because he has none of the typical Cushings signs, for instance very hairy, drinking loads, and as a result peeing loads, and quite often the hollows above their eyes are filled in - my horse had none of these signs but his blood test said he definitely is.
I joined this online group http://pets.groups.yahoo.com/group/EquineCushings/ for help and support for owners of Cushings equines. This is where I learnt that it is the increase in the ACTH in their blood which indicates they are at great risk of laminitis.
They discovered that all horses experience an increase in the ACTH starting late summer and rising until late December. (cant remember what it stands for but find out on the web site) but if a horse has Cushings, it rises much higher and if it is not brought down to "normal" levels, bang, they get hit with laminitis. It is the ACTH which is measured in a blood test to diagnose Cushings.
Please go on this web site for information http://www.ecirhorse.com/
and then join the Cushing group. They have well over 10,000 members now all contributing their experiences and advice on how to manage their diets etc. There are expert moderators on there who will come to your aid if you cannot get the lami under control. No amount of soaking hay/haylage or starving or keeping off grass will help if the ACTH is still very high, the lami will continue until it is brought down.
Have I stressed it enough? It is not the grass that causes the lami in a Cushings horse and if your horse has lami at this time of year it WILL almost certainly have cushings, even if it is under 10 years of age, it is still possible!
 
Good point muff747. :) Testing for Cushings is also important in unexplained laminitis and recurrent symptoms or difficulty in stabilizing.
 
Thanks for the posting and link -very informative. I assumed as my pony is not hairy that he likely could not have cushings, so all great advice for me.
 
ACTH = Adreno-Cortico-Tropic Hormone
Adreno=of the adrenal gland
Cortico=the cortex of the adrenal gland (where cortisol is synthesised)
Tropic=travels toward
Hormone=chemical messenger

I.e. A chemical messenger that travels to, and exerts its primary action in the cortex of the adrenal gland.

Our general policy is that every case of laminitis has at least an insulin level taken, with ACTH as well if >10years old, regardless of summer/winter, or any other (seemingly) obvious cause.
 
And it's Pergolide or Prascend given as a daily (tasteless) tablet that will bring the ACTH levels back down. Although not a cure, this drug works very well in most cases although I understand that the longer a horse has had untreated Cushings, the less likely it is that Pergolide will help. My veteran 27 yr old cob Sunny started displaying some weird symptoms at the start of autumn. I didn't recognise it as Cushings and almost came to the conclusion that his quality of life was too poor. Thank god I got bloods taken and a Cushings test done. Normal ACTH level = 30 ish, Sunny's was 200!!! He was immediately started on 1mg Pergolide daily but it was obvious in just a few days that he was still deteriorating so it was upped to 2mg. Within a week or 2 he was his old self again and a repeat of bloods show his ACTH down to the high end of normal at 30.2. Go onto talkaboutcushings.com and you can register your horse and get a voucher for £15 off the lab test (test usually only about £30 but your vet's time needs to be factored in as well, obviously). Just print it off and hand to your vet.
 
if your horse has lami at this time of year it WILL almost certainly have cushings, even if it is under 10 years of age, it is still possible!

or EMS!

It is the IR symptom of Cushings that causes excessive weeing and drinking! In most cases Pergolide sorts this out too, but EMS and some Cushings also need help from Metfomin to bring levels back to normal
 
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