Swellings after starting pergolide

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maybedaisy

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Anyone seen this after starting Pergolide ?

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I did, these pictures were from last year. Vet told me to reduce to half a tablet and they went down. It's happened to another horse on pergolide so was interested to see if anyone else had the same problem.
 
Just to clarify, vets gave been consulted and have had no previous experience of this. Pergolide does cause swellings in humans and as it's the only drug for cushings there seems to be no appetite to investigate. I found an old entry on another forum where someone's horse had this and wondered if anyone else had the same experience.
 
_HP_ said:
If you or your vet haven't already , you may want to report any side effects to The company that make Prascend
http://www.thelaminitissite.org/articles/please-report-adverse-reactions-to-prascend

Also, you may want to find the Facebook group EMS, PPID (Cushings) and Laminitis UK Facebook group and ask on there. Lots of help and advice on there :)
Click to expand...



Boehringer Ingelheim, the drug company that makes Prascend, would like owners to report any suspected adverse reactions to Prascend, either to your vet (and ensure that he/she reports it), or direct to Boehringer Ingelheim - you can do this as a message on the Talk About Laminitis facebook (where you will also find details about free ACTH testing and free webinars).

If you message BI yourself, please give the name and contact details of your vet, your full name and contact details, the name, age, breed and approximate weight of your horse, the date the treatment started, the dose of Prascend given, the date you noticed the reaction, for how long you noticed the reaction, the outcome and a description of what happened. BI will ensure these reports are followed up and reported to the Veterinary Medicines Directive.
 
Was the horse also on bute at the time?
Taken from The laminitis site....
NB loss of appetite and depression can also be adverse effects of Phenylbutazone (Bute) toxicity:
Myths and Truths About Controlling Pain and Inflammation in Horses
"Gastrointestinal effects are the most important adverse effects of PBZ therapy in horses. Clinical signs include loss of appetite, depression, colic, weight loss, ventral edema, hypoproteinemia (low blood protein), and diarrhea. Hemorrhages and ulcers may occur in the mouth, esophagus, stomach, cecum and right dorsal colon."

Note...ventral edema
 
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