testing for PSSM 2

khalswitz

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Ideally, the original researcher should actively have tried to also disprove their own hypothesis (Popper, falsification), the longer one remains unable to conclusively do so, the more likely the theory is to ‘hold water’. Test and keep testing, particularly the anomalies!
Whether Generatio / Equisec etc have rigorously done this is unclear, insufficient published data, but why the veterinary establishment don’t (appear to) falsify the hypothesis also unclear.
Certainly, plenty of UK vets are dissatisfied with existing biopsy tests for PSSM 2, so other tests for possible links surely worthy of rigorous investigation?
Meanwhile, owners are in despair.
I can tell you why the establishment has appeared to be slow to produce studies falsifying the hypothesis: money.

It’s hard to get equine research funded anyway, let alone when the tests you are testing are patented by someone else and there are already two studies showing no significant associations in two populations so there isn’t novelty in showing no association either. The funders don’t see it as valuable.

The the scientists doing anything to look at these variants are doing it as part of much larger studies (like the Minnesota one) with fairly low priority.

It’s frustrating.
 
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