Pramox side affects?

si_eyes

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I wormed my 18 month old with pramox at the beginning of Oct, I did my 2 year old with same syringe.
a week later, my 18 month old gelding coat went dull/ flakey and he went pretty lifeless to be fair. He also had loose dung. Bloods were taken (inflammation of the gut was result) and He went into oral steroids. He perked up slightly couple weeks later , vet recommended to reduce steroids, 2 days later he was horrifically tucked up, heart rate more than double, slight temp, and lying down a lot.vet straight back out and gave him steroid injection along with vitamin e and antibiotics, more bloods taken. The next day, he had perked up slightly, not half as tucked up and heart rate and temp back to normal. Now today he has went lifeless again and back end looks really weak. Awaiting the second blood results still. Can anyone who has had issues with pramox let me know their symptoms their horse had please? I have heard of foot sore and colic but just wondering if anything similar to what we are going through. Mentioned this to vet n he thought possible, but why didn’t it affect him straight away. Any info appreciated as going through hell for the wee guy and the future is t looking too promising to be honest.
many thanks
 

PinkvSantaboots

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My friend gave it to a yearling and he nearly died similar symptoms to your horse he was in the vets for 3 weeks, my experience is it's not recommended for young horses or anything that has any health issues as it knocks them sideways.

Although I gave it to my big healthy warmblood mare and it made her really ill so it's a wormer I just will not use on anything now.

I hope your horse starts to pick up please let us know how you get on.
 

paddy555

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I'm sorry about your horse and hope he is OK. If you search on here (I see you are new, the search box is in the top RH corner) under pramox. There are several threads and you will find the different experiences and reactions.
Good luck with him.
 

si_eyes

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My friend gave it to a yearling and he nearly died similar symptoms to your horse he was in the vets for 3 weeks, my experience is it's not recommended for young horses or anything that has any health issues as it knocks them sideways.

Although I gave it to my big healthy warmblood mare and it made her really ill so it's a wormer I just will not use on anything now.

I hope your horse starts to pick up please let us know how you get on.
Thank you very much. I will keep this updated. My gelding is such a good boy, really
Hope he is strong enough to fight through this. My vet has been amazing and is out every day, sometimes 3 times a day, giving him all he can. Just have to see what the next set of result are. Poo samples going away tomorrow but I’m the mean time, daily steroid injections are keeping him going
 

si_eyes

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I'm sorry about your horse and hope he is OK. If you search on here (I see you are new, the search box is in the top RH corner) under pramox. There are several threads and you will find the different experiences and reactions.
Good luck with him.
Thank you very much. I have been researching but can’t find any post with exact symptoms described.
thank you muchly again x
 

SEL

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I wormed my 18 month old with pramox at the beginning of Oct, I did my 2 year old with same syringe.
a week later, my 18 month old gelding coat went dull/ flakey and he went pretty lifeless to be fair. He also had loose dung. Bloods were taken (inflammation of the gut was result) and He went into oral steroids. He perked up slightly couple weeks later , vet recommended to reduce steroids, 2 days later he was horrifically tucked up, heart rate more than double, slight temp, and lying down a lot.vet straight back out and gave him steroid injection along with vitamin e and antibiotics, more bloods taken. The next day, he had perked up slightly, not half as tucked up and heart rate and temp back to normal. Now today he has went lifeless again and back end looks really weak. Awaiting the second blood results still. Can anyone who has had issues with pramox let me know their symptoms their horse had please? I have heard of foot sore and colic but just wondering if anything similar to what we are going through. Mentioned this to vet n he thought possible, but why didn’t it affect him straight away. Any info appreciated as going through hell for the wee guy and the future is t looking too promising to be honest.
many thanks

I've known a lot of horror stories with pramox, whilst also using it on a yard of 40 odd horses with only one bad reaction (little cob who had come from a dealer who was probably riddled)

- neuro problems with a late teens quarter horse. May have had a tapeworm burden so could have been die off related. He recovered fine
- loss of protein with a 18 month old colt. That hadn't been particularly healthy since it was born and sadly deteriorated over the following months. I doubt the wormer was to blame but perhaps killing off encysted redworm damaged his gut?
- vet advised someone I knew to use pramox on an underweight yearling. No idea why because it's not recommended for anything underweight with its low safety margin. Yearling was very sick and friend is convinced Pramox was the final straw - hard to tell.

I'm really cautious using it on anything with a known gut problem or youngsters as a result. I'm sorry to hear about your youngster. Both the ones above had pre existing issues so it's impossible to tell whether the wormer was part of the issue. I hope your vet comes up with some answers for you.
 

paddy555

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have you considered sucralfate? My youngster had lawsonia and gut inflamation. He spent time in horse hospital and when he came home although the anti biotics were continued he quickly went downhill. Went back to the hospital and they had also been giving him sucralfate. Started him back on this and there was a great and continuous improvement and it allowed the gut to heal. .
Not suggesting he has lawsonia but just wondering if it is worth asking your vet if he thinks sucralfate will allow the gut to heal.
 
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si_eyes

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have you considered sucralfate? My youngster had lawsonia and gut inflamation. He spent time in horse hospital and when he came home although the anti biotics were continued he quickly went downhill. Went back to the hospital and they had also been giving him sucralfate. Started him back on this and there was a great and continuous improvement and it allowed the gut to heal. .
Not suggesting he has lawsonia but just wondering if it is worth asking your vet if he thinks sucralfate will allow the gut to heal.
The lab first came back with Lawsonia but now they are thinking something else hence now poop samples being sent tomorrow.
I will mention sucralfate to him tomorrow. He was away to give me antibiotics for Lawsonia until the lab said wait and test for something else. Can’t remember what it was tho.
 

si_eyes

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I've known a lot of horror stories with pramox, whilst also using it on a yard of 40 odd horses with only one bad reaction (little cob who had come from a dealer who was probably riddled)

- neuro problems with a late teens quarter horse. May have had a tapeworm burden so could have been die off related. He recovered fine
- loss of protein with a 18 month old colt. That hadn't been particularly healthy since it was born and sadly deteriorated over the following months. I doubt the wormer was to blame but perhaps killing off encysted redworm damaged his gut?
- vet advised someone I knew to use pramox on an underweight yearling. No idea why because it's not recommended for anything underweight with its low safety margin. Yearling was very sick and friend is convinced Pramox was the final straw - hard to tell.

I'm really cautious using it on anything with a known gut problem or youngsters as a result. I'm sorry to hear about your youngster. Both the ones above had pre existing issues so it's impossible to tell whether the wormer was part of the issue. I hope your vet comes up with some answers for you.
Thank you for all this information. I honestly think the wormer is the primary cause of all this but just can’t prove it. Now we are just fighting to get him back to health but looks like it’s not going to be a quick fix. He was honestly perfect before I used pramox, hence I am adamant that is the cause.
 

si_eyes

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Is your vet considering other options too? Just that I would be worried about atypical myopathy, given the time of year.
We have ruled that out yes thank you. Grasssickness was first suspicion but now ruled out also. My vet is looking at all causes and working closely with the lab who is dealing with the samples.
thank you for the suggestion tho, I appreciate all help right now.
 

si_eyes

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This is him after worming.
trying to upload video but it won’t let me
 

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paddy555

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The lab first came back with Lawsonia but now they are thinking something else hence now poop samples being sent tomorrow.
I will mention sucralfate to him tomorrow. He was away to give me antibiotics for Lawsonia until the lab said wait and test for something else. Can’t remember what it was tho.
Lawsonia was difficult to prove. My horse was in horse hospital by this time. he was rushed there as he was very ill. The vet was very experienced with lawsonia, knew he had it but getting an exact result wasn’t,t easy. In the end they told me that even if not the treatment was still the same except with lawsonia the Abs would continue for longer. he had antibiotics for 6 weeks and sucralfate for even longer
 

si_eyes

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Lawsonia was difficult to prove. My horse was in horse hospital by this time. he was rushed there as he was very ill. The vet was very experienced with lawsonia, knew he had it but getting an exact result wasn’t,t easy. In the end they told me that even if not the treatment was still the same except with lawsonia the Abs would continue for longer. he had antibiotics for 6 weeks and sucralfate for even longer
Many thanks again, I will show my vet all this tomorrow. Any help is welcome right now. Especially seeing Lawsonia has been mentioned from the blood results. The only thing that is throwing them is his age. Vet says it’s usually under year old that get it. Lab thought he was 1 year old, not 18 months, hence more testing.
how old was your youngster at the time when he got it?
 

paddy555

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Many thanks again, I will show my vet all this tomorrow. Any help is welcome right now. Especially seeing Lawsonia has been mentioned from the blood results. The only thing that is throwing them is his age. Vet says it’s usually under year old that get it. Lab thought he was 1 year old, not 18 months, hence more testing.
how old was your youngster at the time when he got it?
8 months Rossdales have a leaflet on it. Says youngsters but also odd ones that are older. I think with this it is a case of throwing everything at it as you may never get a 100% answer. .lovely horse, I have everything crossed for him. The thing I learnt was you have to keep on with the meds for a long time, even longer than seems necessary or you relapse
 

si_eyes

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8 months Rossdales have a leaflet on it. Says youngsters but also odd ones that are older. I think with this it is a case of throwing everything at it as you may never get a 100% answer. .lovely horse, I have everything crossed for him. The thing I learnt was you have to keep on with the meds for a long time, even longer than seems necessary or you relapse
Yes I was reading Rossdales today actually. I think that’s what my vet is doing right now, throwing all at him to see what helps and so far it’s the steroid injections, even tho when the lab came back with lawsodia, they said to stop steroids but because they seem to pick him up, my vet has chosen to keep them going until we get more answers. I have to also give him probiotics twice daily for his gut. any thanks again for your time and all your info. I do appreciate it all. Every little bit of information is appreciated to help my wee guy.
 

ycbm

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I really hope your little guy pulls through.

To add to the Pramox stories. I was on a train to go to HOYS one year and got chatting to the person in the next seat. They were a rep for the company that sell Pramox. That person told me that they never used it on their own horses because of the number of adverse reaction reports they got about it.

For general info, for encysted redworm you can give Moxidectin alone as Equest. For tapeworm you can double dose pyrantel, Strongid P, or get praziquantel off the vet (still possible?) or give praziquantel with ivermectin as Eqvalan Duo, which is safer than moxidectin with praziquantel.
.
 

si_eyes

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Hi thanks for that. Yes I know about what to give for worming, unfortunately I just chose pramox this time as have used it many times in the past with no issues.
it is worrying tho that the people who work for the company do not use the product on their own horses. Not a very good sign is it!
many thanks again for your info ?
 

ycbm

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The general info was for everyone reading the thread, not for you. I hope you get the answers you need for your youngster soon.
.
 

Horseysheepy

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I really hope your little guy pulls through.

To add to the Pramox stories. I was on a train to go to HOYS one year and got chatting to the person in the next seat. They were a rep for the company that sell Pramox. That person told me that they never used it on their own horses because of the number of adverse reaction reports they got about it.

For general info, for encysted redworm you can give Moxidectin alone as Equest. For tapeworm you can double dose pyrantel, Strongid P, or get praziquantel off the vet (still possible?) or give praziquantel with ivermectin as Eqvalan Duo, which is safer than moxidectin with praziquantel.
.

Had a horse colic on pramox, so I've always gone by similar to ycbm's system above.
 
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